22LR vs 25 ACP

22LR vs 25 ACP

A side by side look at two common pocket pistol calibers, the 22 LR vs 25 ACP. Which is a better bet for you and for self-defense?

It’s the battle of the mouse guns! In one corner we have the slayer of squirrels, the ravager of rabbits, the one, the only, the 22 LR! In the other corner we have the 25 ACP – once the preferred pistol cartridge of James Bond himself! (He converted to the more powerful 380 ACP by the time Dr. No took place.)

These two rounds share one big thing in common: They are absolutely tiny. On the plus side, that means either one will let you carry a puny pistol. On the down side, neither one is capable of doing a lot of damage as compared to something like the 9mm or 38 Special.

We’re going to assume you want to see how 22LR vs 25 ACP compare as far as self-defense is concerned, because anyone who’d use the 25 ACP for hunting needs a thorough head examination. Let’s compare the cartridges’ ballistic performance, stopping power, recoil, and price and availability so you can determine which one belongs in your purse, pocket or ankle holster!

Cartridge Dimensions

22lr vs 25 acp ammo side by side

 22 LR25 ACP
Case typeRimmed, straightSemi-rimmed, straight
Bullet diameter0.223 in0.251 in
Neck diameter0.226 in0.276 in
Base diameter0.226 in0.278 in
Rim diameter0.278 in0.302 in
Rim thickness0.043 in0.043 in
Case length0.613 in0.615 in
Overall length1.000 in0.91 in
Maximum pressure24,656 psi25,000 psi

These aren’t totally dissimilar cartridges as far as their exterior dimensions are concerned. The 22 LR is a little longer; the 25 ACP is a little wider in diameter (which means its bullet is poised to create an accordingly wider wound channel, terminal expansion notwithstanding). Both are loaded to roughly the same chamber pressure. In short, these two rounds are perfectly sized for the kinds of tiny pistols you’d want as a backup or for when you want to make absolutely sure no one knows you’re carrying.

Although the 22 LR and 25 ACP haven’t got identical dimensions, they can have the same bullet weight. Manufacturers commonly load 22 LR ammo with a 40 grain bullet, while the 25 ACP’s standard is 50 grains. Despite this, 45 grain loads are both available.

These rounds have different types of primers. The 22 LR’s rimfire primer is entirely concealed by cartridge brass; this primer design limits how powerful a cartridge can become, and furthermore makes handloading impractical. The 25 ACP’s Boxer primer is the same that the largest rifle cartridges in the world use – only smaller. Its Boxer primer makes it possible to reload the 25 ACP, but its shell case is so small that you’d need the brains of an adult and the hands of a three-year-old to do it.

22LR vs 25 ACP Ballistics

 22 LR Federal Punch 29gr LFN25 ACP Hornady Critical Defense 35gr FTX22 LR CCI Stinger 32 Gr CPHP25 ACP Winchester Super-X 45 Gr
Muzzle velocity (fps)10809001129815
Velocity @ 25 yds10088501043771
Velocity @ 50 yds952807979730
Velocity @ 75 yds906768928693
Velocity @ 100 yds867732885658
G1 ballistic coefficient0.0860.0670.0850.06
Drop @ 25 yds0.
Drop @ 50 yds-2.13-2.99-1.99-3.65
Drop @ 75 yds-6.67-9.33-6.25-11.38
Drop @ 100 yds-13.85-19.35-13.04-23.64
Muzzle energy (ft lbs)75639166
Energy @ 25 yds65567759
Energy @ 50 yds58516853
Energy @ 75 yds53466148
Energy @ 100 yds48425643

Comparing these two rounds’ ballistic performance based on their available data is tricky. That’s because 22 LR ammo muzzle velocities are almost exclusively recorded with rifles, which have longer barrels that give bullets significantly higher muzzle velocities. Fortunately the Federal Punch and Winchester Silvertip rounds are both designed and marketed for use in pistols, and we already had CCI Stinger pistol data handy.

Let’s be clear, here: You wouldn’t want to use either of these cartridges for self-defense at 100 yards. (You’re not likely to engage a threat that far with a pistol anyway, unless you’re serving in the Armed Forces and you can’t use your rifle.) And at close-range, either one delivers the accuracy you’d need to reliably hit your target (with some practice, of course).

With that, we can safely conclude that the 22 LR delivers a flatter trajectory. It has the faster muzzle velocity, as well as the higher ballistic coefficient (a measure of a bullet’s ability to overcome air resistance in flight, where a higher number is superior). In other words, the 22 LR’s bullet doesn’t drop as quickly as 25 ACP ammo, thus making it easier to aim over longer distances. But more importantly, the 22 LR’s faster bullet does more damage!

25 ACP vs 22 LR: Stopping Power

Stopping power is the product of many factors. Terminal expansion is one of them, but in the case of the 22 LR and the 25 ACP you’re not likely to see much of that, which we’ll demonstrate in a moment. Their bullets lack the velocity and momentum they’d need to expand very reliably. The Federal Punch round is actually engineered around that fact, as the self-defense round’s nickel-plated flat nose bullet is designed solely for penetration and not expansion.

You might expect the rimfire round, which cannot be very powerful by design, to deliver less energy to its target on impact than the Boxer-primed round. To do so would be to underestimate the amazing impotence of the 25 ACP! The 22 LR is often capable of hitting its target harder at 100 yards than the 25 ACP is capable of right out of the muzzle.

This is the key reason we’d have to recommend the 22 LR over the 25 ACP for self-defense. Neither round is a powerhouse. Neither is remotely capable of delivering the minimum 220 ft lbs of energy you’d want for self-defense.

22LR or 25 ACP for Self-Defense?

Testing 22LR vs 25 ACP for self-defense

To demonstrate the relatively weak stopping power each of these calibers deliver, we fired rounds into a block of Clear Ballistics gelatin with a 4-layer cloth barrier. This style of testing is similar to what the Federal Bureau of Investigation does to see the effectiveness of ammo for its officers.

First, we fired the 22LR into the gelatin using a Ruger LCP II.

22Lr fired into ballistic gelatinAs you probably expected, there wasn’t a ton of expansion going on. We fired the Winchester Super-X 22LR ammo into the block and it penetrated about 9-inches. The bullet itself tumbled slightly but didn’t really expand.

To compare against the 25 ACP, we then fired some Speer Gold Dots with a Beretta 950 BS.

Speer Gold Dot 25 ACP ammo fired into gelatinYou can see our Speer Gold Dots expanded a touch more than the 22LR but penetration was even weaker. The 25 ACP ammo only made its way to a penetration of about 8-inches. That’s less than what the FBI considers its minimum distance. Of course, the 22 LR didn’t exactly penetrate like a freight train either. So, if you want your ammo to live up to what the FBI considers “good” – neither of these are great options.

Because of the relatively weak terminal ballistics displayed above, good aim is positively crucial when you’re firing either of these rounds. You NEED a clean shot to the vitals or the head to neutralize a threat as quickly as possible when you’re talking about so small a bullet that carries less than 100 ft lbs of energy. But if the 22 LR can hit almost 50% harder than the 25 ACP, preferring it for personal protection is pretty much a no brainer.

Recoil of the 25 Auto vs 22LR

Recoil is often called “kick.” The less recoil a cartridge generates, the easier it becomes for the shooter to keep their sights trained on the threat. You don’t want to spend any more time lining up your follow-up shots than you have to when someone means to do you immediate bodily harm, right?

Lets compare the objective recoil energy of the six rounds listed above. To do this we only have to factor in muzzle velocity, bullet weight, propellant weight and firearm weight. For simplicity’s sake let’s assume all cartridges have two grains of powder and we’re firing 10 ounce handguns.

22LR vs 25 ACP: Energy Comparison

 Recoil Energy (ft lbs)
22 LR Federal 29gr LFN0.87
22 LR CCI 32gr CPHP1.08
22 LR Winchester 37gr SHP1.23
25 ACP Hornady 35gr FTX0.87
25 ACP Winchester 45gr EP1.11
25 ACP Federal 50gr FMJ1.17

As you might have guessed, both cartridges generate tiny amounts of recoil energy – just over 1 ft lb, which is negligible. There’s no reason to prefer one round over the other as far as recoil is concerned.

Note that next to their small handguns, low recoil is the primary advantage of these small cartridges. They may not be powerful (which is an understatement), but they make it substantially easier to fire a handgun quickly and accurately. While nearly all men can control a 9mm without issue, smaller women may really prefer a round that delivers next to zero quick. If a lady can put 10 rounds of 22 LR inside a threat’s chest and head in a matter of seconds, its low power kind of becomes a moot point!

Price & Availability

Shooting 25 ACP at the range

Subcompact pistols chambered for 22 LR and 25 ACP are both cheap as chips. Such small cartridges aren’t all that expensive, either.

But whereas the 22 LR is the most popular cartridge in the world, and therefore easy to find online or at a gun shop even if you have your eyes closed, the 25 ACP is more of a rarity. You’ll have to go out of your way to get some, and you might have more luck searching for leprechauns during an national crisis.


This is one of the easiest takeaways we’ve ever written: If you want to carry a subcompact pistol and are deciding between 22 LR and 25 ACP, pick 22 LR. Both rounds are accurate enough to cover short distances without fail, and both produce negligible recoil even when fired from small handguns. But a 22 LR handgun is so much more powerful and so much easier to find ammo for that the 25 ACP just doesn’t compete. So, if we have to pick a “winner” in the 22LR vs 25 ACP debate, we’re going with 22 long rifle, based mostly on ammo availability.


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